BDBM50012980 5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]octan-2-one::CHEMBL128329

SMILES O=C1CC2CCC1C(C2c1c[nH]c2ccccc12)N1CCCC1

InChI Key InChIKey=MNUMPEVJOGZKBX-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50012980   

Target5-hydroxytryptamine receptor 2A/2B/2C(Mus musculus (Mouse))
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012980(5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...)
Affinity DataKi:  2.30E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mus musculus (Mouse))
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012980(5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...)
Affinity DataKi:  2.30E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]-ketanserin in mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012980(5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...)
Affinity DataKi:  3.20E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mus musculus (Mouse))
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012980(5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]ketanserin in mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012980(5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in mouse hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012980(5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT in mouse hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mus musculus (Mouse))
Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50012980(5-(1H-Indol-3-yl)-6-pyrrolidin-1-yl-bicyclo[2.2.2]...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 2 receptor by the displacement of [3H]ketanserin in mouse cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed