BDBM50013510 CHEMBL3263773
SMILES COc1ccccc1-c1cc(Nc2cccc(CS(N)(=O)=O)c2)ncn1
InChI Key InChIKey=GGQCIOOSELPMBB-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50013510
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using MBP peptide substrate after 1 hr by FRET-based LANCE assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Hefei University Of Technology
Curated by ChEMBL
Hefei University Of Technology
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human CDK9 using ULight MBP peptide as substrate incubated for 1 hr in presence of ATP by TR-FRET based LANCE assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataIC50: 4.96E+3nMAssay Description:Inhibition of CDK5/p35NCK (unknown origin) using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of full length human recombinant His-tagged CDK9/cyclin T expressed in baculovirus expression system using ULight MBP peptide substrate af...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) using RPPTLSPIPHIPR peptide as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair