BDBM50014485 (S)-2-(4-(((2-(hydroxymethyl)-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)(prop-2-ynyl)amino)benzamido)pentanedioic acid::2-{4-[(2-Hydroxymethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL321977

SMILES OCc1nc2ccc(CN(CC#C)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=AKLRDMIEXNNAPZ-FQEVSTJZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014485   

TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014485((S)-2-(4-(((2-(hydroxymethyl)-4-oxo-3,4-dihydroqui...)
Affinity DataIC50:  100nMAssay Description:Concentration required for in vitro inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Meerut Institute Of Engineering And Technology

Curated by ChEMBL
LigandPNGBDBM50014485((S)-2-(4-(((2-(hydroxymethyl)-4-oxo-3,4-dihydroqui...)
Affinity DataIC50:  98nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014485((S)-2-(4-(((2-(hydroxymethyl)-4-oxo-3,4-dihydroqui...)
Affinity DataIC50:  98nMAssay Description:Concentration of the compound required to inhibit 50% activity of Thymidylate synthase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed