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BDBM50014794 3-[Bis-(4-chloro-phenyl)-methyl]-pyridine::CHEMBL415725

SMILES: Clc1ccc(cc1)C(c1ccc(Cl)cc1)c1cccnc1

InChI Key: InChIKey=AWKPVXLLPWCTIJ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014794   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)		BDBM50014794
PNG
(3-[Bis-(4-chloro-phenyl)-methyl]-pyridine | CHEMBL...)
Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)c1cccnc1
Show InChI InChI=1S/C18H13Cl2N/c19-16-7-3-13(4-8-16)18(15-2-1-11-21-12-15)14-5-9-17(20)10-6-14/h1-12,18H
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Article
PubMed
n/an/an/an/a 84n/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome

J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair