BDBM50014815 Bis-(4-chloro-phenyl)-pyrimidin-5-yl-methanol::CHEMBL29904

SMILES OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1

InChI Key InChIKey=CSRYTZCLFTYZLS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014815   

TargetAromatase(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50014815(Bis-(4-chloro-phenyl)-pyrimidin-5-yl-methanol | CH...)
Affinity DataEC50:  71nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50014815(Bis-(4-chloro-phenyl)-pyrimidin-5-yl-methanol | CH...)
Affinity DataEC50:  71nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed