BDBM50014823 (E)-4-Hydroxy-6-{2-[2-isopropyl-6-phenyl-4-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-vinyl}-tetrahydro-pyran-2-one::CHEMBL2368193

SMILES CC(C)c1nc(cc(-c2ccc(cc2)C(F)(F)F)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1

InChI Key InChIKey=PHESDKOISSFXQV-ITWZMISCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014823   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50014823((E)-4-Hydroxy-6-{2-[2-isopropyl-6-phenyl-4-(4-trif...)
Affinity DataIC50:  36nMAssay Description:In vitro inhibition of rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed