BDBM50014826 (E)-6-{2-[4,6-Bis-(4-fluoro-phenyl)-2-isopropyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368202
SMILES CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccc(F)cc1
InChI Key InChIKey=HTIWAOOZGHNHMJ-CXYUPCIPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50014826
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst
Curated by ChEMBL
Hoechst
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of cellular HMG-CoA reductase in cultures of human HEP G2 cells, determined by decreased incorporation of sodium [14C]-acetate into choles...More data for this Ligand-Target Pair