BDBM50014832 (E)-6-{2-[2-Ethyl-4-(4-fluoro-phenyl)-6-phenyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368195

SMILES CCc1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1

InChI Key InChIKey=JZCAAARUYARJOI-DDVDASKDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014832   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50014832((E)-6-{2-[2-Ethyl-4-(4-fluoro-phenyl)-6-phenyl-pyr...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed