BDBM50015547 CHEMBL3265335

SMILES [H][C@]12COCC[C@]1([H])[C@]1(COC(N)=N1)c1cc(ccc1O2)-c1cncc(Cl)c1

InChI Key InChIKey=BGRWOLNAPSRJIS-UCLAIMLFSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015547   

TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50:  130nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed