BDBM50016983 CHEMBL3220543

SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2C(O)=O)c1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(SC)n1

InChI Key InChIKey=MATQWNLSVRLACV-VUGDMWQRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016983   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50016983(CHEMBL3220543)
Affinity DataIC50:  6nMAssay Description:Inhibition of N-terminal His-tagged full length human 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50016983(CHEMBL3220543)
Affinity DataIC50:  82nMAssay Description:Inhibition of N-terminal His-tagged full length rat 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50016983(CHEMBL3220543)
Affinity DataIC50:  310nMAssay Description:Inhibition of N-terminal His-tagged full length mouse 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed