BindingDB logo
myBDB logout

BDBM50017664 CHEMBL3288678

SMILES: Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccc2cn[nH]c2c1)-c1ccccc1

InChI Key: InChIKey=QHONKXLBFJJVRB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017664   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM50017664
PNG
(CHEMBL3288678)
Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccc2cn[nH]c2c1)-c1ccccc1
Show InChI InChI=1S/C24H17N5O/c1-28-23-13-21(15-5-3-2-4-6-15)27-29(23)22-12-17(9-10-19(22)24(28)30)16-7-8-18-14-25-26-20(18)11-16/h2-14H,1H3,(H,25,26)
PDB

Reactome pathway

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEBI
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...


Bioorg Med Chem Lett 24: 2693-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.04.051
BindingDB Entry DOI: 10.7270/Q228094H
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50017664
PNG
(CHEMBL3288678)
Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccc2cn[nH]c2c1)-c1ccccc1
Show InChI InChI=1S/C24H17N5O/c1-28-23-13-21(15-5-3-2-4-6-15)27-29(23)22-12-17(9-10-19(22)24(28)30)16-7-8-18-14-25-26-20(18)11-16/h2-14H,1H3,(H,25,26)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

CHEBI
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...


Bioorg Med Chem Lett 24: 2693-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.04.051
BindingDB Entry DOI: 10.7270/Q228094H
More data for this
Ligand-Target Pair