BDBM50017686 4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide::CHEMBL421665::Fluperamide

SMILES CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)c(c1)C(F)(F)F)(c1ccccc1)c1ccccc1

InChI Key InChIKey=WPYGCZCMGMVGNO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017686   

TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50017686(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50017686(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataKi:  2.15E+3nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50017686(4-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy...)
Affinity DataIC50:  280nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed