BDBM50018741 4,7,8,9,10,10a-Hexahydro-5H-thieno[2,3-a]quinolizine::CHEMBL346016

SMILES C1CCN2CCc3ccsc3C2C1

InChI Key InChIKey=JDQPKNAZHYFPQE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018741   

TargetAlpha-2A adrenergic receptor(BOVINE)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018741(4,7,8,9,10,10a-Hexahydro-5H-thieno[2,3-a]quinolizi...)
Affinity DataKi:  195nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]-clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018741(4,7,8,9,10,10a-Hexahydro-5H-thieno[2,3-a]quinolizi...)
Affinity DataKi:  195nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]-clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018741(4,7,8,9,10,10a-Hexahydro-5H-thieno[2,3-a]quinolizi...)
Affinity DataKi:  1.10E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018741(4,7,8,9,10,10a-Hexahydro-5H-thieno[2,3-a]quinolizi...)
Affinity DataKi:  1.10E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed