BDBM50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755
SMILES CCCN(CCC)C1CCc2ccc(O)cc2C1
InChI Key InChIKey=BLYMJBIZMIGWFK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 64 hits for monomerid = 50020222
Affinity DataKi: 1.20nMAssay Description:Tested for binding affinity against dopamine receptor D3 expressed in Sf9 cells.More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Tested in vitro for the inhibition of [3H]-U-86,170 binding to Dopamine receptor D3, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 2.35nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.35nMAssay Description:Displacement of [3H]spiperone from cloned dopamine D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Tested in vitro for the inhibition of [3H]-raclopride binding to Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibitory activity against [125I]- NCQ298 binding to dopamine receptor D3 in Sf 9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Tested for the inhibitory activity against Dopamine D3 receptor in infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Tested for inhibition of the binding of [125I]NCQ298 to dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.19nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.19nMAssay Description:Displacement of [3H]Spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.19nMAssay Description:Displacement of [3H]spiperone from rat D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 23.2nMAssay Description:Tested for the inhibitory activity against sigma receptor rat cerebellarMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Tested in vitro for the inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of the radioligand [3H]-spiperone from D2 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 72.7nMAssay Description:Tested for the inhibitory activity against 5-hydroxytryptamine 1A receptor in rat hippocampalMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKi: 73nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [125I]trans-8-OH-PIPAT in membrane homogenates of hippocampal tissue ...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 142nMAssay Description:Tested for the inhibitory activity against D2H (high-affinity states) receptor in infected HEK 293 cells.More data for this Ligand-Target Pair
Affinity DataKi: 142nMAssay Description:Tested for inhibition of the binding of [125I]NCQ298 to D2 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 142nMAssay Description:Inhibitory activity against [125I]- NCQ298 binding to dopamine receptor D2 in Sf 9 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 143nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 148nMAssay Description:Tested in vitro for the inhibition of [3H]-spiperone binding to Dopamine receptor D4, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 202nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 311nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 311nMAssay Description:Displacement of [3H]Spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 311nMAssay Description:Displacement of [3H]spiperone from rat D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.43E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2long receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL