BindingDB logo
myBDB logout

BDBM50021060 CHEMBL3287649

SMILES: Fc1ccc(NC(=O)[C@@H]2CCCC[C@@H]2NCc2c[nH]c3ccccc23)cc1

InChI Key: InChIKey=ALZKIEOFIQKKKY-CTNGQTDRSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021060   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50021060
PNG
(CHEMBL3287649)
Show SMILES Fc1ccc(NC(=O)[C@@H]2CCCC[C@@H]2NCc2c[nH]c3ccccc23)cc1
Show InChI InChI=1S/C22H24FN3O/c23-16-9-11-17(12-10-16)26-22(27)19-6-2-4-8-21(19)25-14-15-13-24-20-7-3-1-5-18(15)20/h1,3,5,7,9-13,19,21,24-25H,2,4,6,8,14H2,(H,26,27)/t19-,21+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
16n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]SS14 from human SST3 expressed in CHO membrane after 60 to 90 mins by scintillation counting


ACS Med Chem Lett 5: 690-5 (2014)


Article DOI: 10.1021/ml500079u
BindingDB Entry DOI: 10.7270/Q22N53V4
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50021060
PNG
(CHEMBL3287649)
Show SMILES Fc1ccc(NC(=O)[C@@H]2CCCC[C@@H]2NCc2c[nH]c3ccccc23)cc1
Show InChI InChI=1S/C22H24FN3O/c23-16-9-11-17(12-10-16)26-22(27)19-6-2-4-8-21(19)25-14-15-13-24-20-7-3-1-5-18(15)20/h1,3,5,7,9-13,19,21,24-25H,2,4,6,8,14H2,(H,26,27)/t19-,21+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 20n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human SST3 expressed in CHO-K1 cells assessed as foreskin-stimulated cAMP accumulation after 45 mins by TR-FRET assay


ACS Med Chem Lett 5: 690-5 (2014)


Article DOI: 10.1021/ml500079u
BindingDB Entry DOI: 10.7270/Q22N53V4
More data for this
Ligand-Target Pair