BDBM50021259 CHEMBL3287906

SMILES COc1nc2cccnc2n1[C@@H]1C[C@@H](C1)Nc1nc2ccccc2s1

InChI Key InChIKey=QSZCDYHTHAAFAW-TXEJJXNPSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021259   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50021259(CHEMBL3287906)Copy SMILESCopy InChI

Affinity DataIC50:  3.40nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate after 1 hr by IMAP-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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