BDBM50021545 2-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol::2-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol(2-FPE)::CHEMBL302451

SMILES CNCC(O)c1cccc(O)c1F

InChI Key InChIKey=KFHINOFEYCZOKN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50021545   

TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50021545(2-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol ...)
Affinity DataKi:  1.20E+3nMAssay Description:Compound was tested for its ability to displace [3H]clonidine form alpha-2 adrenergic receptor site in guinea pig cerebral cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021545(2-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol ...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021545(2-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol ...)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021545(2-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol ...)
Affinity DataKi:  1.70E+4nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed