BDBM50021920 4-(1,2,3,5,6,10b-Hexahydro-pyrrolo[2,1-a]isoquinolin-6-yl)-benzonitrile;HCl::CHEMBL35441

SMILES N#Cc1ccc(cc1)[C@@H]1CN2CCC[C@@H]2c2ccccc12

InChI Key InChIKey=MEFHMLXHQQALTE-RBUKOAKNSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021920   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021920(4-(1,2,3,5,6,10b-Hexahydro-pyrrolo[2,1-a]isoquinol...)
Affinity DataKi:  7.90nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021920(4-(1,2,3,5,6,10b-Hexahydro-pyrrolo[2,1-a]isoquinol...)
Affinity DataKi:  14nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021920(4-(1,2,3,5,6,10b-Hexahydro-pyrrolo[2,1-a]isoquinol...)
Affinity DataKi:  83nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed