BDBM50022000 CHEMBL2371853::Pro-His-Pro-Phe-His-Statine-Val-Tyr-NH2

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1)[C@@H](O)CC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=AACGSANRMWSOFJ-VOSVLFMFSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50022000   

TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022000(CHEMBL2371853 | Pro-His-Pro-Phe-His-Statine-Val-Ty...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022000(CHEMBL2371853 | Pro-His-Pro-Phe-His-Statine-Val-Ty...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory potency on plasma renin obtained from Sprague-Dawley ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022000(CHEMBL2371853 | Pro-His-Pro-Phe-His-Statine-Val-Ty...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibitory activity against rat plasma renin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022000(CHEMBL2371853 | Pro-His-Pro-Phe-His-Statine-Val-Ty...)
Affinity DataIC50:  37nMAssay Description:Inhibitory potency on plasma renin obtained from hypertensive humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022000(CHEMBL2371853 | Pro-His-Pro-Phe-His-Statine-Val-Ty...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022000(CHEMBL2371853 | Pro-His-Pro-Phe-His-Statine-Val-Ty...)
Affinity DataIC50:  100nMAssay Description:Inhibitory potency on plasma renin obtained from New Zealand white rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022000(CHEMBL2371853 | Pro-His-Pro-Phe-His-Statine-Val-Ty...)
Affinity DataIC50:  10nMAssay Description:Inhibitory potency on plasma renin obtained from mongrel dogsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed