BDBM50023025 CHEMBL3144145::{1-[1-[1-(2-Cyclohexylsulfanyl-1-hydroxy-ethyl)-3-methyl-butylcarbamoyl]-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-naphthalen-2-yl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)C[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)OC(C)(C)C)[C@H](O)CSC1CCCCC1

InChI Key InChIKey=SUPOWGINMOGKBY-ZBHOMJLCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023025   

TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50023025(CHEMBL3144145 | {1-[1-[1-(2-Cyclohexylsulfanyl-1-h...)
Affinity DataIC50:  40nMAssay Description:The compound was tested for inhibition of human renal renin at the pH optimum 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed