BDBM50023092 Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide::Boc-Phe-His-Sta-Leu-(-)-1,2-diphenylthylamide::Boc-Phe-His-Sta-Leu-(-)-alpha-phenylthylamide::CHEMBL53112

SMILES CC(C)CC(NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CC(=O)N[C@@H](CC(C)C)C(=O)NC(Cc1ccccc1)c1ccccc1

InChI Key InChIKey=RDIHBRMRBRGJRM-KNNFAOMSSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50023092   

TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  20nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  27nMAssay Description:Inhibition of hog kidney renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  28nMAssay Description:Inhibition of hog kidney renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  29nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  36nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  68nMAssay Description:Inhibition of hog kidney renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  68nMAssay Description:Inhibition of human plasma renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  700nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023092(Boc-Phe-His-Sta-Leu-(+)-1,2-diphenylthylamide | Bo...)
Affinity DataKi:  700nMAssay Description:Inhibition of hog kidney renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed