BDBM50023229 CHEMBL3329755
SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1
InChI Key InChIKey=FJPQEOQGIZSLES-UHFFFAOYSA-N
Data 12 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50023229
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activity at human muscarinic acetylcholine receptor subtype 4 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 2.10E+3nMAssay Description:Activity at human muscarinic acetylcholine receptor subtype 3 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activity at human muscarinic acetylcholine receptor subtype 2 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 5.40E+3nMAssay Description:Activity at human muscarinic acetylcholine receptor subtype 1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(RAT)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 610nMAssay Description:Activity at rat muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Positive allosteric modulation of M5 AchR (unknown origin) assessed as increase in acetylcholine-induced responseMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(RAT)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 3.10E+3nMAssay Description:Activity at rat muscarinic acetylcholine receptor subtype 3 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(RAT)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activity at rat muscarinic acetylcholine receptor subtype 2 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Activity at rat muscarinic acetylcholine receptor subtype 1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 195nMAssay Description:Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activity at rat muscarinic acetylcholine receptor subtype 4 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair