BDBM50023924 CHEMBL3325507

SMILES CN1CCC(CC1)NC(=O)c1ccc(COc2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=IVOIYPHGIHJNMU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50023924   

TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50023924(CHEMBL3325507)
Affinity DataIC50:  105nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50023924(CHEMBL3325507)
Affinity DataIC50:  105nMAssay Description:Reversible inhibition of recombinant human GlyT2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake after 2 hrs by top count assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50023924(CHEMBL3325507)
Affinity DataIC50:  105nMAssay Description:Inhibition of human GlyT-2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed