BDBM50025708 2-[6-(1-Carbamoyl-ethylsulfanyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylsulfanyl]-propionamide::CHEMBL78636

SMILES CC(Sc1nc(SC(C)C(N)=O)c2cnn(-c3ccccc3)c2n1)C(N)=O

InChI Key InChIKey=CGFRTQAGVQLSNN-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50025708   

TargetAdenosine receptor A2a(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50025708(2-[6-(1-Carbamoyl-ethylsulfanyl)-1-phenyl-1H-pyraz...)
Affinity DataKi:  146nMAssay Description:Binding affinity towards Adenosine A2a receptor by inhibition of [3H]-CGS-21,680 binding to rat brain striatum membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50025708(2-[6-(1-Carbamoyl-ethylsulfanyl)-1-phenyl-1H-pyraz...)
Affinity DataKi:  229nMAssay Description:Binding affinity for Adenosine A1 receptor by inhibition of [3H]-PIA binding to whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50025708(2-[6-(1-Carbamoyl-ethylsulfanyl)-1-phenyl-1H-pyraz...)
Affinity DataKi:  370nMAssay Description:Binding affinity against adenosine A1 receptor in rat brain membrane using N6-[3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50025708(2-[6-(1-Carbamoyl-ethylsulfanyl)-1-phenyl-1H-pyraz...)
Affinity DataIC50:  1.03E+3nMAssay Description:Binding affinity against adenosine A1 receptor in rat brain membrane preparations using N6-[3H]-cyclohexyladenosine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed