BDBM50025937 CHEMBL3144417::{1-[1-{3-[1-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-1-cyclohexylmethyl-2-hydroxy-propylcarbamoyl}-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid ethyl ester

SMILES CCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=AGSXLSIXECZYEP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025937   

TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025937(CHEMBL3144417 | {1-[1-{3-[1-(1-Carbamoyl-2-phenyl-...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025937(CHEMBL3144417 | {1-[1-{3-[1-(1-Carbamoyl-2-phenyl-...)
Affinity DataIC50:  0.760nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025937(CHEMBL3144417 | {1-[1-{3-[1-(1-Carbamoyl-2-phenyl-...)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed