BDBM50025976 3-Chloro-2-(1H-tetrazol-5-yl)-chromen-4-one::CHEMBL168453

SMILES Clc1c(oc2ccccc2c1=O)-c1nnn[nH]1

InChI Key InChIKey=LPKGQHBYVFYNTI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50025976   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025976(3-Chloro-2-(1H-tetrazol-5-yl)-chromen-4-one | CHEM...)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025976(3-Chloro-2-(1H-tetrazol-5-yl)-chromen-4-one | CHEM...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in 30 -70% (NH4)2SO4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025976(3-Chloro-2-(1H-tetrazol-5-yl)-chromen-4-one | CHEM...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in 30 -70% (NH4)2SO4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025976(3-Chloro-2-(1H-tetrazol-5-yl)-chromen-4-one | CHEM...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025976(3-Chloro-2-(1H-tetrazol-5-yl)-chromen-4-one | CHEM...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at time 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed