BDBM50026924 8-[4-(4-Phenyl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL296254

SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ccccc1

InChI Key InChIKey=NSXIWGZHXBZYNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026924   

TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026924(8-[4-(4-Phenyl-piperazin-1-yl)-butyl]-8-aza-spiro[...)
Affinity DataIC50:  430nMAssay Description:Inhibition of [3H]spiperone binding to dopamine receptor from rat corpus striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50026924(8-[4-(4-Phenyl-piperazin-1-yl)-butyl]-8-aza-spiro[...)
Affinity DataIC50:  15nMAssay Description:In vitro binding affinity of the compound against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT in human CYP3A4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed