BDBM50027808 (Dynorphin)2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-5-guanidino-pentanoylamino)-5-guanidino-pentanoylamino]-3-methyl-pentanoic acid::2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-5-guanidino-pentanoylamino)-5-guanidino-pentanoylamino]-3-methyl-pentanoic acid::CHEMBL268984::Dynorphin B

SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=WRPLGMBDXVBPEG-FLUOCFNGSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50027808   

TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50027808((Dynorphin)2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydro...)
Affinity DataKi:  11.4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50027808((Dynorphin)2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydro...)
Affinity DataKi:  39.8nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50027808((Dynorphin)2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydro...)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50027808((Dynorphin)2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydro...)
Affinity DataKi:  241nMAssay Description:Tested for binding affinity by [3H]diprenorphine displacement for Opioid receptor delta 1 are carried on crude membrane fractions obtained from the w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50027808((Dynorphin)2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydro...)
Affinity DataKi:  1.35E+3nMAssay Description:Tested for binding affinity by [3H]diprenorphine displacement for Opioid receptor mu 1 was carried on crude membrane fractions obtained from the whol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed