BDBM50028867 (3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-propyl)-azetidin-2-one::CHEMBL23541::SCH-47949::SCH-48461

SMILES COc1ccc(cc1)[C@@H]1[C@@H](CCCc2ccccc2)C(=O)N1c1ccc(OC)cc1

InChI Key InChIKey=IMNTVVOUWFPRSB-JWQCQUIFSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50028867   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50028867((3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-pro...)
Affinity DataIC50:  1.80E+4nMAssay Description:Concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity using microsomal ACAT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028867((3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-pro...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028867((3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-pro...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50028867((3R,4S)-1,4-Bis-(4-methoxy-phenyl)-3-(3-phenyl-pro...)
Affinity DataIC50:  1.10E+4nMAssay Description:The concentration required for 50% inhibition of Acyl coenzyme A:cholesterol acyltransferase activity was measured at the dosage by using microsomal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed