BDBM50030282 CHEBI:51052::Lucanthone

SMILES CCN(CC)CCNc1ccc(C)c2sc3ccccc3c(=O)c12

InChI Key InChIKey=FBQPGGIHOFZRGH-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030282   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50030282(CHEBI:51052 | Lucanthone)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human APE1 after 25 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50030282(CHEBI:51052 | Lucanthone)
Affinity DataKd:  89nMAssay Description:Binding affinity to full length human APE1 expressed in Escherichia coli BL21/DE3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50030282(CHEBI:51052 | Lucanthone)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of full length human APE1 expressed in Escherichia coli BL21/DE3 assessed as inhibition of incision of depurinated supercoiled pUC18 plasm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank