BDBM50030630 (RS)-1-aminoindan-1,5-dicarboxylic acid::1-Amino-indan-1,5-dicarboxylic acid::1-Amino-indan-1,5-dicarboxylic acid(RS-AIDA)::AIDA::AIDC::CHEMBL313938::GNF-Pf-1401

SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O

InChI Key InChIKey=LSTPKMWNRWCNLS-UHFFFAOYSA-N

Data  10 KI  3 IC50

Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50030630   

TargetMetabotropic glutamate receptor 1(RAT)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi:  98.3nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi:  1.10E+3nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi:  7.00E+3nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche Inc

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi:  2.14E+5nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi: >1.00E+6nMAssay Description:Antagonist potency against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche Inc

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataIC50: 7.00E+3nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataIC50: 2.14E+5nMAssay Description:Inhibitory concentration of the compound for half maximal inhibition of PI hydrolysis (mGluR1a)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030630((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...)
Show SMILES NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
Affinity DataIC50: 2.14E+5nMAssay Description:Compound was tested for functional response of human metabotropic glutamate receptor mGluR1-alpha expressed in AV-12 cells by measuring inhibitory co...More data for this Ligand-Target Pair