BDBM50031201 (S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarbonyl)-benzoylamino]-3-methyl-butyryl}-pyrrolidine-2-carboxylic acid ((S)-3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-amide::CHEMBL340818

SMILES CC(C)[C@H](NC(=O)c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(Cl)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F

InChI Key InChIKey=YGPYJEFIYYPEEE-HJOGWXRNSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031201   

TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031201((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031201((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)
Affinity DataIC50:  34nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed