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BDBM50032104 CHEMBL92137::N*2*-Phenethyl-N*4*-o-tolyl-quinazoline-2,4-diamine::TCMDC-142322

SMILES: Cc1ccccc1Nc1nc(NCCc2ccccc2)nc2ccccc12

InChI Key: InChIKey=QCQACOBJADYRJQ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032104   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium-transporting ATPase


(Sus scrofa (Pig))
BDBM50032104
PNG
(CHEMBL92137 | N*2*-Phenethyl-N*4*-o-tolyl-quinazol...)
Show SMILES Cc1ccccc1Nc1nc(NCCc2ccccc2)nc2ccccc12
Show InChI InChI=1S/C23H22N4/c1-17-9-5-7-13-20(17)25-22-19-12-6-8-14-21(19)26-23(27-22)24-16-15-18-10-3-2-4-11-18/h2-14H,15-16H2,1H3,(H2,24,25,26,27)
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Similars

Article
PubMed
n/an/a 810n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals R&D

Curated by ChEMBL


Assay Description
Inhibition of K+ stimulated gastric ATPase activity


J Med Chem 38: 2763-73 (1995)


Article DOI: 10.1021/jm00014a027
BindingDB Entry DOI: 10.7270/Q2TT4Q0J
More data for this
Ligand-Target Pair