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BDBM500331 US11021478, Example 16

SMILES: OC(=O)CNC(=O)C1=C(O)C2(CCCC2)n2c(ccc2C1=O)C1CC1

InChI Key: InChIKey=FYHAFIDITYJSOV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 500331   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))
BDBM500331
PNG
(US11021478, Example 16)
Show SMILES OC(=O)CNC(=O)C1=C(O)C2(CCCC2)n2c(ccc2C1=O)C1CC1
Show InChI InChI=1S/C18H20N2O5/c21-13(22)9-19-17(25)14-15(23)12-6-5-11(10-3-4-10)20(12)18(16(14)24)7-1-2-8-18/h5-6,10,24H,1-4,7-9H2,(H,19,25)(H,21,22)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 600n/an/an/an/an/an/a



KIND PHARMACEUTICAL

US Patent


Assay Description
Activities of HIF prolyl hydroxylase was determined according to the method as described in Anal Biochem, 2004, 330: 74-80, which was slightly modifi...


US Patent US11021478 (2021)

More data for this
Ligand-Target Pair