Found 18 hits for monomerid = 50033383 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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Similars
| DrugBank Article PubMed
| 0.760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre Fabre
Curated by ChEMBL
| Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]-5-CT radioligand |
Bioorg Med Chem Lett 8: 675-80 (1999)
Article DOI: 10.1016/s0960-894x(98)00090-0 BindingDB Entry DOI: 10.7270/Q24B30F8 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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Similars
| DrugBank Article PubMed
| 0.920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre Fabre
Curated by ChEMBL
| Assay Description Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alpha |
J Med Chem 38: 3602-7 (1995)
Article DOI: 10.1021/jm00018a020 BindingDB Entry DOI: 10.7270/Q25M66C2 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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| DrugBank Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre Fabre
Curated by ChEMBL
| Assay Description Binding affinity for cloned human 5-hydroxytryptamine 1D receptor beta |
J Med Chem 38: 3602-7 (1995)
Article DOI: 10.1021/jm00018a020 BindingDB Entry DOI: 10.7270/Q25M66C2 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
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Similars
| DrugBank Article PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre Fabre
Curated by ChEMBL
| Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1B receptor using [3H]-5-CT radioligand |
Bioorg Med Chem Lett 8: 675-80 (1999)
Article DOI: 10.1016/s0960-894x(98)00090-0 BindingDB Entry DOI: 10.7270/Q24B30F8 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
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| Article PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre Fabre
Curated by ChEMBL
| Assay Description Binding affinity for cloned human 5-hydroxytryptamine 1A receptor |
J Med Chem 38: 3602-7 (1995)
Article DOI: 10.1021/jm00018a020 BindingDB Entry DOI: 10.7270/Q25M66C2 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
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| Article PubMed
| 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre Fabre
Curated by ChEMBL
| Assay Description In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand |
Bioorg Med Chem Lett 8: 675-80 (1999)
Article DOI: 10.1016/s0960-894x(98)00090-0 BindingDB Entry DOI: 10.7270/Q24B30F8 |
More data for this Ligand-Target Pair | |
Multidrug resistance-associated protein 4
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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Similars
| Article PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc
Curated by ChEMBL
| Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... |
Toxicol Sci 136: 216-41 (2013)
Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D |
More data for this Ligand-Target Pair | |
Canalicular multispecific organic anion transporter 2
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc
Curated by ChEMBL
| Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ... |
Toxicol Sci 136: 216-41 (2013)
Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D |
More data for this Ligand-Target Pair | |
Canalicular multispecific organic anion transporter 1
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc
Curated by ChEMBL
| Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... |
Toxicol Sci 136: 216-41 (2013)
Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
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Similars
| Article PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc
Curated by ChEMBL
| Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ... |
Toxicol Sci 136: 216-41 (2013)
Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D |
More data for this Ligand-Target Pair | |
Serotonin (5-HT) receptor
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome
Curated by ChEMBL
| Assay Description Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptor |
J Med Chem 44: 681-93 (2001)
Article DOI: 10.1021/jm000956k BindingDB Entry DOI: 10.7270/Q2PC354M |
More data for this Ligand-Target Pair | |
Serotonin (5-HT) receptor
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre Fabre
Curated by ChEMBL
| Assay Description Effective concentration of the compound determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor... |
Bioorg Med Chem Lett 8: 675-80 (1999)
Article DOI: 10.1016/s0960-894x(98)00090-0 BindingDB Entry DOI: 10.7270/Q24B30F8 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a |
Wellcome Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay. |
J Med Chem 38: 3566-80 (1995)
Article DOI: 10.1021/jm00018a016 BindingDB Entry DOI: 10.7270/Q2GF0SJ4 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
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Patents
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| Article PubMed
| n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a |
Wellcome Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 1 receptor using rabbit jugular vein assay in the absence of endothelium |
J Med Chem 38: 3566-80 (1995)
Article DOI: 10.1021/jm00018a016 BindingDB Entry DOI: 10.7270/Q2GF0SJ4 |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(RAT) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
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Patents
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| Article PubMed
| n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a |
Wellcome Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against dopamine receptor D1 in rat striatum using [3H]-SCH-23,390 as radioligand |
J Med Chem 38: 3566-80 (1995)
Article DOI: 10.1021/jm00018a016 BindingDB Entry DOI: 10.7270/Q2GF0SJ4 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a |
Wellcome Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay. |
J Med Chem 38: 3566-80 (1995)
Article DOI: 10.1021/jm00018a016 BindingDB Entry DOI: 10.7270/Q2GF0SJ4 |
More data for this Ligand-Target Pair | |
Serotonin (5-HT) receptor
(Homo sapiens (Human)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
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| DrugBank Article PubMed
| n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome
Curated by ChEMBL
| Assay Description Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptor |
J Med Chem 44: 681-93 (2001)
Article DOI: 10.1021/jm000956k BindingDB Entry DOI: 10.7270/Q2PC354M |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM50033383
 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar
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CHEBI CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a |
Wellcome Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against Dopamine receptor D2 in rat striatum using [3H]-spiperone as radioligand |
J Med Chem 38: 3566-80 (1995)
Article DOI: 10.1021/jm00018a016 BindingDB Entry DOI: 10.7270/Q2GF0SJ4 |
More data for this Ligand-Target Pair | |