BDBM50034440 CHEMBL286682::N-(3,4-Dimethyl-isoxazol-5-yl)-4-propylamino-benzenesulfonamide
SMILES CCCNc1ccc(cc1)S(=O)(=O)Nc1onc(C)c1C
InChI Key InChIKey=ARYCFFYGDKYENL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50034440
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Ability to inhibit [125I]-ET1 binding to vascular smooth muscle (vsm)- A10 cellsMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair