BDBM50034683 (S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL41929

SMILES COC(=[OH+])C1=C(C)N=C(C)C([C@H]1c1cccc(c1)[N+]([O-])=O)=C([O-])OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=OCBZSBUOYIQXSP-XIFFEERXSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50034683   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  0.160nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  0.160nMAssay Description:Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +++:highly activeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  55nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  100nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  330nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  420nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  530nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  2.80E+3nMAssay Description:Binding affinity against cloned human adenosine A3 receptor by radioligand binding assay using [125I]-AB-MECA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [125 I]AB-MECA from human Adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [125]AB-MECA binding to human Adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-CGS-21,680 from Adenosine A2A receptor of rat striatal membrane at 10e-4 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against adenosine A1 receptor in rat cerebral cortex membrane by radioligand binding assay using [3H](R)-PIA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50034683((S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-py...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from Adenosine A1 receptor of rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed