BDBM50034936 5-Methyl-6-{[prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl}-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL49454
SMILES COc1cc(cc(OC)c1OC)N(CC#C)Cc1cnc2nc(N)nc(N)c2c1C
InChI Key InChIKey=HWTHGASACLWVQR-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50034936
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 11.8nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 53.5nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 11.8nMAssay Description:Inhibitory activity against Dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair