BDBM50035730 3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL87031::methyl 3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)c(Cl)c1)N2C
InChI Key InChIKey=AMIHUYQKNJHXPT-UHFFFAOYSA-N
Data 23 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50035730
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 27.6nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Ability to inhibit [3H]citalopram binding to serotonin transporter in cynomolgus monkey striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]3-beta-(4-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to dopamine transporter of cynomolgus monkey striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter (5-HT) in monkey caudate-putamen.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Binding affinity at the Serotonin transporter in rat midbrain by inhibition of 0.5 nM [3H]-paroxetine bindingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 0.790nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Binding affinity at the Norepinephrine transporter in rat frontal cortex by inhibition of 0.5 nM [3H]nisoxetine bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 358nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in cynomolgus (macaca fascicularis) monkey caudate putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 1.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 2.47nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 2.47nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter (5-HT) in monkey caudate-putamen.More data for this Ligand-Target Pair