BDBM50036058 CHEMBL354883::benzyl (S)-1-((S)-2-(((S)-1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)carbamoyl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate::{(S)-2-Methyl-1-[(S)-2-((S)-3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-pyrrolidine-1-carbonyl]-propyl}-carbamic acid benzyl ester
SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F
InChI Key InChIKey=FVOBWOKIKIDXMP-FHWLQOOXSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50036058
Affinity DataKi: 1.60nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE) catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala- Ala-Pro-Val-pNMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibitory activity against Human Neutrophil Elastase using acute lung injury model (ALIM) assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity against human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:In vitro inhibitory activity against human leukocyte elastase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity for human leukocyte elastaseMore data for this Ligand-Target Pair