BDBM50036079 2-(8-Cyano-1-oxo-3-phenyl-1,9-dihydro-beta-carbolin-2-yl)-N-(3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-acetamide::CHEMBL176540

SMILES CC(C)C(NC(=O)Cn1c(O)c2nc3c(cccc3c2cc1-c1ccccc1)C#N)C(=O)C(F)(F)F

InChI Key InChIKey=SNUVFAAECMQWDW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036079   

TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036079(2-(8-Cyano-1-oxo-3-phenyl-1,9-dihydro-beta-carboli...)
Affinity DataKi:  6.60nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE) mediated hydrolysis of the synthetic substrate MeOSuc-Ala-Ala-Pro-Val-pNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036079(2-(8-Cyano-1-oxo-3-phenyl-1,9-dihydro-beta-carboli...)
Affinity DataKi:  180nMAssay Description:Inhibitory activity against bovine chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed