BDBM50036251 CHEMBL141265::[(1S,2R)-3-(Benzenesulfonyl-isobutyl-amino)-1-benzyl-2-hydroxy-propyl]-carbamic acid benzyl ester
SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)S(=O)(=O)c1ccccc1
InChI Key InChIKey=KRKOLCVTGDIAEB-RRPNLBNLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50036251
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Binding affinity of the compound for HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against HIV-1 protease in spectrofluorometric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Ability of the compound to inhibit HIV-1 protease was determined using spectrofluorometric assayMore data for this Ligand-Target Pair