BDBM50037218 1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman-7-yl)-cyclopentanecarboxylic acid::CHEMBL51770::CP-105696
SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)C1(CCCC1)C(O)=O
InChI Key InChIKey=KMNLXCBYBKHKSK-BKMJKUGQSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50037218
Affinity DataIC50: 5.60nMAssay Description:Inhibition of leukotriene B4 (LTB4) binding to guinea pig spleenMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Compound was evaluated for its ability to inhibit [3H]LTB4 binding to LTB4 receptors on guinea pig spleen membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of leukotriene B4 (LTB4) binding to guinea pig spleenMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LTB4 receptor induced chemotaxis of isolated human neutrophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LTB4 receptor induced chemotaxis of isolated human neutrophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of LTB4 receptor induced chemotaxis of isolated human neutrophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 30.3nMAssay Description:Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Tested for binding activity against [3H]-LTB4 to whole human neutrophil with halh maximal inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
Affinity DataIC50: 7.67E+4nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of leukotriene B4 (LTB4) binding to guinea pig spleenMore data for this Ligand-Target Pair