BDBM50037775 CHEMBL121204::Thiophene-2-carboxylic acid [2-(6-amino-purin-9-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yl]-amide

SMILES Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1NC(=O)c1cccs1

InChI Key InChIKey=IRSWQOTVSIGUSL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037775   

TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037775(CHEMBL121204 | Thiophene-2-carboxylic acid [2-(6-a...)
Affinity DataIC50:  5.00E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037775(CHEMBL121204 | Thiophene-2-carboxylic acid [2-(6-a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50037775(CHEMBL121204 | Thiophene-2-carboxylic acid [2-(6-a...)
Affinity DataIC50:  2.40E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed