BDBM50037814 2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol::CHEMBL121093

SMILES OCC1NC(CO)C(O)C1O

InChI Key InChIKey=PFYHYHZGDNWFIF-UHFFFAOYSA-N

Data  1 KI  8 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50037814   

TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataKi:  9.10E+5nMAssay Description:Inhibition constant against Alpha-FucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-galactosidase(Bos taurus (Bovine))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataIC50:  3.30E+3nMAssay Description:Concentration that causes 50% inhibition of mammalian cytosolic beta-galactosidase was determined in bovine liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataIC50:  9.20E+4nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-glucosidase (lysosomal) was determined in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Bos taurus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataIC50:  3.60E+3nMAssay Description:Concentration that causes 50% inhibition of mammalian lactase beta-galactosidase was determined in rat intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrehalase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataIC50:  3.60E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian trehalase was determined in rat intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral alpha-glucosidase C(Mus musculus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataIC50:  9.10E+4nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-glucosidase (isomaltase) was determined in rat intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrehalase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataIC50:  2.00E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian trehalase was determined in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50037814(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Affinity DataIC50:  3.40E+4nMAssay Description:Concentration that causes 50% inhibition of mammalian cellobiase beta-glucosidase was determined in rat intestineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed