BDBM50038171 7-Chloro-4-hydroxy-3-[3-(thiophen-3-yloxy)-phenyl]-1H-quinolin-2-one::CHEMBL32076

SMILES Oc1c(-c2cccc(Oc3ccsc3)c2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key InChIKey=ASDUOZQLLPOESZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038171   

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038171(7-Chloro-4-hydroxy-3-[3-(thiophen-3-yloxy)-phenyl]...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed