BDBM50038691 CHEMBL58579::[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-methyl-amine

SMILES CNCCc1c[nH]c2ccc(OC)cc12

InChI Key InChIKey=NFDDCRIHMZGWBP-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038691   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50038691(CHEMBL58579 | [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-...)
Affinity DataKi:  4.10nMAssay Description:Affinity against 5-hydroxytryptamine 2A receptor (D) labeled with [125I]-DOI.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50038691(CHEMBL58579 | [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-...)
Affinity DataKi:  450nMAssay Description:Affinity against 5-hydroxytryptamine 2A receptor (K) labeled with [3H]-ketanserin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50038691(CHEMBL58579 | [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-...)
Affinity DataKi:  840nMAssay Description:Affinity against 5-hydroxytryptamine 2C receptor in J1 cells transfected with the rat 5-HT2C gene labeled with [3H]-mesulergine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidade Estadual Paulista (Unesp)

Curated by ChEMBL
LigandPNGBDBM50038691(CHEMBL58579 | [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of Electric eel AChE assessed as amount of thiocholine released using acetylthiocholine iodide as substrate after 6 mins by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed