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BDBM50039189 1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid 2-diethylamino-ethoxymethyl ester::CHEMBL75217

SMILES: CCN(CC)CCOCOC(=O)C1(CCCCC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=OPZQMZXXMIXWON-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039189   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50039189
PNG
(1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid...)
Show SMILES CCN(CC)CCOCOC(=O)C1(CCCCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H29Cl2NO3/c1-3-23(4-2)12-13-25-15-26-19(24)20(10-6-5-7-11-20)16-8-9-17(21)18(22)14-16/h8-9,14H,3-7,10-13,15H2,1-2H3
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antibodypedia
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PC cid
PC sid
UniChem

Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Binding affinity towards muscarinic m1 receptor


J Med Chem 37: 2285-91 (1994)


Article DOI: 10.1021/jm00041a006
BindingDB Entry DOI: 10.7270/Q29S1RPS
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50039189
PNG
(1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid...)
Show SMILES CCN(CC)CCOCOC(=O)C1(CCCCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H29Cl2NO3/c1-3-23(4-2)12-13-25-15-26-19(24)20(10-6-5-7-11-20)16-8-9-17(21)18(22)14-16/h8-9,14H,3-7,10-13,15H2,1-2H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
22n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Binding affinity towards muscarinic m2 receptor


J Med Chem 37: 2285-91 (1994)


Article DOI: 10.1021/jm00041a006
BindingDB Entry DOI: 10.7270/Q29S1RPS
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(RAT)
BDBM50039189
PNG
(1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid...)
Show SMILES CCN(CC)CCOCOC(=O)C1(CCCCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H29Cl2NO3/c1-3-23(4-2)12-13-25-15-26-19(24)20(10-6-5-7-11-20)16-8-9-17(21)18(22)14-16/h8-9,14H,3-7,10-13,15H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
22n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Tested for its binding affinity towards sigma-1 site in rat brain using E3H1-(+)-SKF 10047 as radioligand in rat brain


J Med Chem 37: 2285-91 (1994)


Article DOI: 10.1021/jm00041a006
BindingDB Entry DOI: 10.7270/Q29S1RPS
More data for this
Ligand-Target Pair