BDBM50040362 8-Amino-7-benzyl-1,3-bis-cyclopropylmethyl-3,7-dihydro-purine-2,6-dione::CHEMBL142782

SMILES Nc1nc2n(CC3CC3)c(=O)n(CC3CC3)c(=O)c2n1Cc1ccccc1

InChI Key InChIKey=OLQNFXOLYGKUAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040362   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040362(8-Amino-7-benzyl-1,3-bis-cyclopropylmethyl-3,7-dih...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of adenosine binding to A1 receptorof rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040362(8-Amino-7-benzyl-1,3-bis-cyclopropylmethyl-3,7-dih...)
Affinity DataIC50:  840nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 microM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed