BDBM50040371 1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)-8-[1-methyl-pyrrolidin-(2Z)-ylideneamino]-3,7-dihydro-purine-2,6-dione::CHEMBL144196

SMILES COc1ccc(Cn2c(N=C3CCCN3C)nc3n(CC4CC4)c(=O)n(CC4CC4)c(=O)c23)cc1

InChI Key InChIKey=NQNCGLJSKXRTET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040371   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040371(1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)-8-[...)
Affinity DataIC50:  610nMAssay Description:Inhibition of adenosine binding to A1 receptorof rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040371(1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)-8-[...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 microM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed